2-Bromo-5-(trifluoromethyl)aniline

Names

[ CAS No. ]:
454-79-5

[ Name ]:
2-Bromo-5-(trifluoromethyl)aniline

[Synonym ]:
5-(Trifluoromethyl)-2-bromoaniline
2-bromo-5-trifluoromethylphenylamine
Benzenamine, 2-bromo-5-(trifluoromethyl)-
1-amino-2-bromo-5-(trifluoromethyl)benzene
2-AMINO-4-TRIFLUOROMETHYLBROMOBENZENE
2-BROMO-5-(TRIFLUOROMETHYL)ANILIME
2-Bromo-5-(trifluoromethyl)benzenamine
2-Bromo-5-(trifluoro
EINECS 207-227-6
2-Bromo-5-trifluoromethylaniline
6-Bromo-α,α,α-trifluoro-m-toluidine
2-bromo-5(trifluoromethyl)aniline
MFCD00007637
2-amino-4-trifluoromthylbromobenzene
2-Bromo-5-(trifluoromethyl)aniline
3-Amino-4-bromobenzotrifluoride
ZR BE EXFFF
4-BROMO-3-AMINOBENZOTRIFLUORIDE

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
243.1±40.0 °C at 760 mmHg

[ Melting Point ]:
47-49°C

[ Molecular Formula ]:
C₇H₅BrF₃N

[ Molecular Weight ]:
240.020

[ Flash Point ]:
100.8±27.3 °C

[ Exact Mass ]:
238.955734

[ PSA ]:
26.02000

[ LogP ]:
3.40

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.522

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S27-S36/37/39-S45-S37/39

[ RIDADR ]:
UN 3267 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2921420090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety.

Bioorg. Med. Chem. 16(6) , 2955-67, (2008)

Inhibition of the hepatitis C virus (HCV) NS3 protease has emerged as an attractive approach to defeat the global hepatitis C epidemic. In this work, we present the synthesis and biochemical evaluatio...