Coenzyme M

[ Density]:
1.8±0.1 g/cm3

[ Molecular Formula ]:
C₄H₁₀O₆S₄

[ Molecular Weight ]:
282.379

[ Exact Mass ]:
281.936005

[ PSA ]:
176.10000

[ LogP ]:
-1.83

[ Index of Refraction ]:
1.637

[ HS Code ]:
2930909090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.

Cancer Chemother. Pharmacol. 67(2) , 381-91, (2011)

Previous studies from our laboratory have identified a role for gamma-glutamyl transpeptidase (GGT) in BNP7787 (disodium 2,2'-dithio-bis ethane sulfonate, dimesna, Tavocept™)-mediated cisplatin nephro...

Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303).

J. Thorac. Oncol. 3(10) , 1159-65, (2008)

We investigated dose-dense docetaxel and cisplatin in patients with measurable non-small cell lung cancer in a randomized phase II study without [A] or with [B] a putative chemoprotective agent, BNP77...

New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

Cancer Chemother. Pharmacol. 52 Suppl 1 , S3-15, (2003)

Any approach applied to drug discovery and development by the medical community and pharmaceutical industry has a direct impact on the future availability of improved, novel, and curative therapies fo...

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