AG-205
Names
Biological Activity
[Description]:
(rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C22H23ClN6OS
[ Molecular Weight ]:
454.97600
[ Exact Mass ]:
454.13400
[ PSA ]:
92.45000
[ LogP ]:
3.55360