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Methenolone Acetate

Names

[ CAS No. ]:
434-05-9

[ Name ]:
Methenolone Acetate

[Synonym ]:
Primobolan
Methenolone acetate
Primonabol
EINECS 207-097-0
Androst-1-en-3-one, 17-(acetyloxy)-1-methyl-, (5α)-
(5α)-1-Methyl-3-oxoandrost-1-en-17-yl acetate
Nibal
MFCD00864181
Methenolone (acetate)

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
441.2±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H32O3

[ Molecular Weight ]:
344.488

[ Flash Point ]:
189.9±28.8 °C

[ Exact Mass ]:
344.235138

[ PSA ]:
43.37000

[ LogP ]:
4.93

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.536

[ Storage condition ]:
2~8℃

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BV8408500
CHEMICAL NAME :
5-alpha-Androst-1-en-3-one, 17-beta-hydroxy-1-methyl-, acetate
CAS REGISTRY NUMBER :
434-05-9
LAST UPDATED :
199309
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C22-H32-O3
MOLECULAR WEIGHT :
344.54
WISWESSER LINE NOTATION :
L E5 B666 OV LUTJ A1 E1 FOV1 K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
200 mg/kg
SEX/DURATION :
male 10 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
60 mg/kg
SEX/DURATION :
female 17-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
AVBIB9 Advances in the Biosciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1967- Volume(issue)/page/year: 13,71,1974

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2942000000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2942000000


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