(Deamino-Cys1,Val4,D-Arg8)-Vasopressin

Names

[ Name ]:
(Deamino-Cys1,Val4,D-Arg8)-Vasopressin

[Synonym ]:
Val4-dDAVP
[deamino-Cys1,Val4,D-Arg8]-vasopressin
DVDAVP
3-MERCAPTOPROPIONYL-TYR-PHE-VAL-ASN-CYS-PRO-D-ARG-GLY-NH2
[MPR1,VAL4,DARG8] VASOPRESSIN
1-Deamino-4-L-valine-8D-arginine vasopressin
dVDAVP,(Val4)-DesMopressin
2-Deamino-L-Cys(1)-L-Tyr-L-Phe-L-Val-L-Asn-L-Cys(1)-L-Pro-D-Arg-Gly-NH2
3-MERCAPTOPROPIONYL-TYR-PHE-VAL-ASN-CYS-PRO-ARG-GLY-NH2
1-deamino-4-valine-8-D-arginine-vasopressin
MPR-TYR-PHE-VAL-ASN-CYS-PRO-DARG-GLY-NH2

Biological Activity

[Description]:

[Deamino-4-valine, 8-D-arginine]-Vasopressin (dVDAVP) is a highly potent and specific antidiuretic agent possessing protracted effects[1][2].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> Others >> Others

[References]

[1]. M Manning, et al. [1-deaminopenicillamine,4-valine]-8-D-arginine-vasopressin, a highly potent inhibitor of the vasopressor response to arginine-vasopressin. J Med Chem. 1977 Sep;20(9):1228-30.

[2]. M Manning, et al. Solid phase synthesis of (1-deamino,4-valine)-8-D-arginine-vasopressin (DVDAVP), a highly potent and specific antidiuretic agent possessing protracted effects. J Med Chem. 1973 Sep;16(9):975-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₆₅N₁₃O₁₁S₂

[ Molecular Weight ]:
1040.22000

[ Exact Mass ]:
1039.44000

[ PSA ]:
442.92000

[ LogP ]:
2.21370

Synthetic Route

Click to get detail synthetic route

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.