Procyanidin A2

Names

[ Name ]:
Procyanidin A2

[Synonym ]:
Procyanidin A2
7,4beta-&Procyanidol A2
8)-epicatechin
(2r,3r,8s,14r,15r)-2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-2h,14h-8,14-methanochromeno[7,8-d][1,3]benzodioxocine-3,5,11,13,15-pentol
Proanthocyanidin A-2
Proanthocyanidin A2
Epicatechin-(2beta-&Procyanidin dimer A2
Dimeric catechin

Biological Activity

[Description]:

Procyanidin A2 is a flavonoid found in cranberries and lingonberries, with anti-cancer, antioxidant, antimicrobial and anti-inflammation activity[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Bacterial[1]

[In Vitro]

Procyanidin A2 shows DPPH radical scavenging activity, with an IC50 of 5.08 ± 0.37 μM[1].

[References]

[1]. LingrongWen, et al. Identification of flavonoids in litchi (Litchi chinensis Sonn.) leaf and evaluation of anticancer activities. Journal of Functional Foods. January 2014, 6, P: 555-563.

[2]. Coleman SL, et al. Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells. Int J Mol Sci. 2016 Nov 12;17(11).

Chemical & Physical Properties

[ Density]:
1.766g/cm3

[ Boiling Point ]:
946ºC at 760 mmHg

[ Molecular Formula ]:
C₃₀H₂₄O₁₂

[ Molecular Weight ]:
576.50

[ Flash Point ]:
525.9ºC

[ Exact Mass ]:
576.12700

[ PSA ]:
209.76000

[ LogP ]:
2.79350

[ Index of Refraction ]:
1.829

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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