Catharanthine Tartrate

Names

[ Name ]:
Catharanthine Tartrate

[Synonym ]:
Ibogamine-18-carboxylic acid, 3,4-didehydro-, methyl ester, (5ξ,18ξ)-, 2,3-dihydroxybutanedioate (2:1) (salt)
(2R,3R)-2,3-Dihydroxysuccinic acid - methyl (2α,5β,18β)-3,4-didehydroibogamine-18-carboxylate (1:2)
Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate

Biological Activity

[Description]:

Catharanthine Tartrate is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

[References]

[1]. Jadhav A, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₆H₅₄N₄O₁₀

[ Molecular Weight ]:
822.942

[ Exact Mass ]:
822.383972

[ Storage condition ]:
2-8°C

Related Compounds

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