3-Fucosyllactose

Names

[ Name ]:
3-Fucosyllactose

Biological Activity

[Description]:

3-Fucosyllactose (3-Fucosyl-D-lactose) is one of the major fucosylated oligosaccharides found in human breast milk. 3-Fucosyllactose shows prebiotic, immunomodulator, neonatal brain development, and antimicrobial function[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

3-Fucosyllactose (3-Fucosyl-D-lactose) (10 mg/mL) can inhibit the adhesion of enteric and respiratory pathogens to the human epithelial cell lines Caco-2 and A549[2].

[References]

[1]. Choi YH, et al. Biosynthesis of the human milk oligosaccharide 3-fucosyllactose in metabolically engineered Escherichia coli via the salvage pathway through increasing GTP synthesis and β-galactosidase modification. Biotechnol Bioeng. 2019 Dec;116(12):3324-3332.

[2]. Weichert S, et al. Bioengineered 2'-fucosyllactose and 3-fucosyllactose inhibit the adhesion of Pseudomonas aeruginosa and enteric pathogens to human intestinal and respiratory cell lines. Nutr Res. 2013 Oct;33(10):831-8.

Chemical & Physical Properties

[ Density]:
1.73g/cm3

[ Boiling Point ]:
803.2ºC at 760 mmHg

[ Melting Point ]:
>165°C (dec.) (lit.)

[ Molecular Formula ]:
C₁₈H₃₂O₁₅

[ Molecular Weight ]:
488.43800

[ Flash Point ]:
439.6ºC

[ Exact Mass ]:
488.17400

[ PSA ]:
248.45000

[ Vapour Pressure ]:
7.55E-30mmHg at 25°C

[ Index of Refraction ]:
1.652

Safety Information

[ WGK Germany ]:
3

Related Compounds

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