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pf-61

Names

[ CAS No. ]:
4075-42-7

[ Name ]:
pf-61

[Synonym ]:
nci 144-144

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
890.2ºC at 760 mmHg

[ Molecular Formula ]:
C42H56N2O12

[ Molecular Weight ]:
780.90000

[ Flash Point ]:
492.2ºC

[ Exact Mass ]:
780.38300

[ PSA ]:
204.55000

[ LogP ]:
5.42580

[ Index of Refraction ]:
1.635

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KD1921000
CHEMICAL NAME :
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2H)-dione, 5,6,9,17,19,21- hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy -8-(1-pyrrolidinylmet hyl)-, 21-acetate
CAS REGISTRY NUMBER :
4075-42-7
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C42-H56-N2-O12
MOLECULAR WEIGHT :
781.00

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CMTRAG Chemotherapia. (Basel, Switzerland) V.1-12, 1960-67. For publisher information, see CHTHBK. Volume(issue)/page/year: 12,155,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
190 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
38KLAC "Structure-Activity Relationship among the Semisynthetic Antibiotics," Perlman, D., ed., New York, Academic Press, 1977 Volume(issue)/page/year: -,531,1977

Related Compounds

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