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Torcitabine

Names

[ CAS No. ]:
40093-94-5

[ Name ]:
Torcitabine

[Synonym ]:
2'-deoxy-cytidine
L-Deoxycytidine
2'-desoxycytidine

Biological Activity

[Description]:

Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> HBV

[In Vitro]

Torcitabine (2'-Deoxy-L-cytidine) shows greater inhibition of first strand than second strand DNA synthesis[2].

[References]

[1]. Buti M, et al. Drugs in development for hepatitis B. Drugs. 2005;65(11):1451‐1460.

[2]. Keam SJ. Telbivudine. Drugs. 2007;67(13):1917‐1929.

Chemical & Physical Properties

[ Density]:
1.73 g/cm3

[ Boiling Point ]:
497.6ºC at 760 mmHg

[ Molecular Formula ]:
C9H13N3O4

[ Molecular Weight ]:
227.21700

[ Flash Point ]:
254.8ºC

[ Exact Mass ]:
227.09100

[ PSA ]:
110.60000

[ Index of Refraction ]:
1.719

[ Storage condition ]:
-20°C

Synthetic Route

Precursor & DownStream