20-Hydroxyganoderic acid G

Names

[ Name ]:
20-Hydroxyganoderic acid G

Biological Activity

[Description]:

20-Hydroxyganoderic Acid G is a lanostane triterpenoid obtained from the EtOH extract of fruiting bodies of the Ganoderma curtisii. 20-Hydroxyganoderic Acid G inhibits BV-2 microglia cells activated by LPS with an IC50 of 21.33 μM. 20-Hydroxyganoderic Acid G has therapeutic potential in the drug discovery of nerve inflammation diseases associated with microglia activated by LPS[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Jiao Y, et al. Lanostane triterpenoids from Ganoderma curtisii and their NO production inhibitory activities of LPS-induced microglia. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3556-61.

Chemical & Physical Properties

[ Density]:
1.31±0.1 g/cm3(Predicted)

[ Boiling Point ]:
760.1±60.0 °C(Predicted)

[ Molecular Formula ]:
C₃₀H₄₄O₉

[ Molecular Weight ]:
548.67

Related Compounds

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