SCH-12679 MALEATE
Names
[ CAS No. ]:
39624-66-3
[ Name ]:
SCH-12679 MALEATE
[Synonym ]:
TREPIPAM MALEATE
R(-)-1-Phenyl-2,3,4,5-tetrahydro-1H-7,8-dimethoxy-3-benzazepine
Chemical & Physical Properties
[ Boiling Point ]:
416.8ºC at 760 mmHg
[ Molecular Formula ]:
C23H26NO6
[ Molecular Weight ]:
412.45600
[ Flash Point ]:
137.5ºC
[ Exact Mass ]:
412.17600
[ PSA ]:
99.13000
[ LogP ]:
1.63860
Safety Information
Articles
Prog. Clin. Biol. Res. 167 , 137-56, (1984)
Effects of the phenethylamine derivatives, BL-3912, fenfluramine, and Sch-12679, in rats trained with LSD as a discriminative stimulus.
Psychopharmacology 68(2) , 159-62, (1980)
Six rats were trained to discriminate the effects of LSD (100 micrograms/kg) and saline in a two-lever choice task. They were then tested with each of three phenethylamine derivatives, BL-3912 (2,5-di...
Pharmacological evaluation of SCH-12679: evidence for an in vivo antagonism of D1-dopamine receptors.J. Pharmacol. Exp. Ther. 252 , 558-567, (1990)
The benzazepine compound SCH-12679 has been shown to have clinical efficacy against aggressive behavior in mentally deficient patients. The purpose of the present investigation was to evaluate the pot...