N-Cbz-L-Glutamic acid 5-tert-butyl ester

Names

[ Name ]:
N-Cbz-L-Glutamic acid 5-tert-butyl ester

[Synonym ]:
(2S)-2-{[(Benzyloxy)carbonyl]amino}-5-tert-butoxy-5-oxopentanoic acid (non-preferred name)
5-tert-butyl ester
MFCD00038274
EINECS 223-421-3
N-Carbobenzoxy-L-glutamic Acid 5-tert-Butyl Ester
(S)-2-(((Benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid
N-Benzyloxycarbonyl-L-glutamic acid gamma-tert-butyl ester
N-Cbz-L-Glutamic acid 5-tert-butyl ester
5-tert-Butyl N-Cbz-L-glutamate
(2S)-2-{[(Benzyloxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoate
Cbz-L-glutamic acid 5-tert-butyl ester
(2S)-2-{[(Benzyloxy)carbonyl]amino}-5-tert-butoxy-5-oxopentanoate
5-tert-Butyl N-Carbobenzoxy-L-glutamate
5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester, ion(1-)
(2S)-2-{[(Benzyloxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid
L-Glutamic acid, N-[(phenylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester

Biological Activity

[Description]:

Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, drug, compounds synthesis[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Shaomeng Wang, et al. Small molecule stat protein degraders. WO2021195481A1 (compound A)

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
522.6±50.0 °C at 760 mmHg

[ Melting Point ]:
83-87ºC

[ Molecular Formula ]:
C₁₇H₂₃NO₆

[ Molecular Weight ]:
337.368

[ Flash Point ]:
269.9±30.1 °C

[ Exact Mass ]:
337.152527

[ PSA ]:
101.93000

[ LogP ]:
3.43

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.524

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38-43

[ Safety Phrases ]:
26-36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%