1,4-Dichloro(2H4)benzene

Names

[ Name ]:
1,4-Dichloro(2H4)benzene

[Synonym ]:
1,4-dichloro-2,3,5,6-tetradeuteriobenzene
MFCD00000605
1,4-Dichloro(H)benzene
Tetradeutero-1,4-dichlorobenzene
1,4-Dichloro-2,3,5,6-tetradeuterobenzene
Benzene-1,2,4,5-d, 3,6-dichloro-

Biological Activity

[Description]:

1,4-Dichlorobenzene-d4 is the deuterium labeled 1,4-Dichlorobenzene[1]. 1,4-Dichlorobenzene is used as an intermediate product in the manufacture of pigments, pesticides and disinfectants. 1,4-Dichlorobenzene is also employed as a moth control agent[2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. M. Tschickardt. Dichlorobenzene isomers (1,2-dichlorobenzene, 1,3-dichlorobenzene and 1,4 dichlorobenzene).

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
174.1±0.0 °C at 760 mmHg

[ Melting Point ]:
52-54ºC(lit.)

[ Molecular Formula ]:
C₆Cl₂D₄

[ Molecular Weight ]:
151.027

[ Flash Point ]:
65.6±0.0 °C

[ Exact Mass ]:
149.994110

[ LogP ]:
3.34

[ Vapour Pressure ]:
1.6±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.549

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07, GHS08, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H351-H410

[ Precautionary Statements ]:
P280-P305 + P351 + P338

[ Target Organs ]:
Blood, Central nervous system, Liver

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
36/37-46-60-61-45-24/25-23

[ RIDADR ]:
UN 3077 9

[ WGK Germany ]:
3

[ Packaging Group ]:
III

Precursor & DownStream

Precursor

DownStream

Articles

Elements and polycyclic aromatic hydrocarbons in exhaust particles emitted by light-duty vehicles.

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The main purpose of this work was to evaluate the chemical composition of particulate matter (PM) emitted by eight different light-duty vehicles. Exhaust samples from petrol and diesel cars (Euro 3 to...