Acetamide, 2-chloro-N-[5,6,7,9-tetrahydro-1,2, 3-trimethoxy-10-(methylthio)-9-oxobenz[a]heptalen-7-yl]-, (S)-
Names
[ CAS No. ]:
38479-08-2
[ Name ]:
Acetamide, 2-chloro-N-[5,6,7,9-tetrahydro-1,2, 3-trimethoxy-10-(methylthio)-9-oxobenz[a]heptalen-7-yl]-, (S)-
[Synonym ]:
17-Chloro-10-demethoxy-10-methylthiocolchicine
Chemical & Physical Properties
[ Density]:
1.33g/cm3
[ Boiling Point ]:
749.2ºC at 760 mmHg
[ Molecular Formula ]:
C22H24ClNO5S
[ Molecular Weight ]:
449.94800
[ Flash Point ]:
406.9ºC
[ Exact Mass ]:
449.10600
[ PSA ]:
99.16000
[ LogP ]:
4.19470
[ Index of Refraction ]:
1.615
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AB5839000
- CHEMICAL NAME :
- Acetamide, 2-chloro-N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(m ethylthio)-9-oxobenzo (a) heptalen-7-yl)-, (S)-
- CAS REGISTRY NUMBER :
- 38479-08-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C22-H24-Cl-N-O5-S
- MOLECULAR WEIGHT :
- 449.98
- WISWESSER LINE NOTATION :
- L B677 MV&T&J CO1 DO1 EO1 JMV1G NS1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1007 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981
Related Compounds
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