l-n-methylephedrine hydrochloride

Controlled Substances

Psychoactive Drugs/Narcotic Drugs/Hypertoxic Chemicals/Non-Medical Use of Narcotic Drugs and Psychotropic Substances

Names

[ Name ]:
l-n-methylephedrine hydrochloride

[Synonym ]:
l-methylephedrinehydrochloride
N-METHYL EPHEDRINE HCL
METHYLEPHEDRINE HCL
(1R,2S)-2-dimethylamino-1-phenyl-propan-1-ol,hydrochloride
(IR,2S)-I-N-Methylephedrine HCL
(1R,2S)-2-dimethylamino-1-phenylpropanol hydrochloride
L-Methyl
L-Methyl ephedrine
methyf
(-)-methylephedrinehydrochloride
(1R,2S)(-)-methylephedrinium chloride
(1R,2S)-2-Dimethylamino-1-phenyl-propan-1-ol,Hydrochlorid
n-methylephedrinehydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
251.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₈ClNO

[ Molecular Weight ]:
215.72000

[ Flash Point ]:
96.9ºC

[ Exact Mass ]:
215.10800

[ PSA ]:
23.47000

[ LogP ]:
2.47210

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA4795490

CHEMICAL NAME :: Benzenemethanol, alpha-(1-(dimethylamino)ethyl)-, hydrochloride, (R-(R*,S*))-

CAS REGISTRY NUMBER :: 38455-90-2

LAST UPDATED :: 199312

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C11-H17-N-O.Cl-H

MOLECULAR WEIGHT :: 215.75

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 216 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,1117,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 699 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 53,638,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 144 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 54,688,1958

Safety Information

[ HS Code ]:
2939490010

Customs

[ HS Code ]: 2939490010