2',3'-O-Isopropylidene-5-hydroxyMethyl uridine

Names

[ Name ]:
2',3'-O-Isopropylidene-5-hydroxyMethyl uridine

[Synonym ]:
2',3'-O-isopropylidene-5-hydroxymethyluridine
5-hydroxymethyl-2',3'-O-isopropylideneuridine
5-hydroxymethyl-2',3'-isopropylidene-uridine
5-hydroxymethyl-O2',O3'-isopropylidene-uridine
1-(2,3-O-isopropylidene-β-D-ribofuranosyl)-5-hydroxy-methyluracil

Biological Activity

[Description]:

5-(Hydroxymethyl)-2′,3′-O-(1-methylethylidene)uridine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₈N₂O₇

[ Molecular Weight ]:
314.29

[ Exact Mass ]:
314.11100

[ PSA ]:
123.01000

Related Compounds

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