RBC6

Names

[ Name ]:
RBC6

[Synonym ]:
6-Amino-4-(3,5-dichloro-2-hydroxyphenyl)-3-propyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(3,5-dichloro-2-hydroxyphenyl)-2,4-dihydro-3-propyl-

Biological Activity

[Description]:

RBC6 is an inhibitor of GTPases RalA. RBC6 inhibits binding of Ral to its effector RALBP1. RBC6 also inhibits Ral-mediated cell spreading of murine embryonic fibroblasts, as well as anchorage-independent growth of human cancer celllines[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Yan C, et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20;515(7527):443-7.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
544.8±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₁₄Cl₂N₄O₂

[ Molecular Weight ]:
365.214

[ Flash Point ]:
283.3±30.1 °C

[ Exact Mass ]:
364.049377

[ LogP ]:
3.75

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.691

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.