Hyaluronidase

Names

[ Name ]:
Hyaluronidase

[Synonym ]:
2,4-Bis(1,3-benzodioxol-5-yl)-4-oxobutanoic acid
Neopermease
1,3-Benzodioxole-5-butanoic acid, α-1,3-benzodioxol-5-yl-γ-oxo-
Hydase
EINECS 253-464-3
Hyaluronoglucosidase
MFCD00131351
Hyaluronoglucosaminidase
Chondroitinase

Biological Activity

[Description]:

Hyaluronidase (Hyaluronate 4-glycanohydrolase; Hyaluronoglucosaminidase) is a naturally occurring enzyme that depolymerizes hyaluronic acid by cleavage of glycosidic bonds and has been used as a local anesthetic additive[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Vartanian AJ, et al. Injected hyaluronidase reduces restylane-mediated cutaneous augmentation. Arch Facial Plast Surg. 2005 Jul-Aug;7(4):231-7.

[2]. Brandon E, et al. The Use of Hyaluronidase in Cosmetic Dermatology: A Review of the Literature. J Clin Investigat Dermatol. 2015;3(2): 7.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
598.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₄O₇

[ Molecular Weight ]:
342.300

[ Flash Point ]:
223.2±23.6 °C

[ Exact Mass ]:
342.073944

[ LogP ]:
2.41

[ Appearance of Characters ]:
powder | yellow-brown

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.642

[ Storage condition ]:
−20°C

[ Water Solubility ]:
Soluble in water, practically insoluble in acetone and in anhydrous ethanol

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

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