Thymidine-5'-Triphosphoric Acid

Names

[ CAS No. ]:
365-08-2

[ Name ]:
Thymidine-5'-Triphosphoric Acid

[Synonym ]:
2'-deoxythymidine 5'-triphosphate
THYMIDINE 5'-TRIPHOSPHATE
Thymidine-5'-Triphosphoric Acid

Biological Activity

[Description]:

Deoxythymidine-5'-triphosphate (dTTP), a deoxynucleotide, can be used in deoxyribonucleic acid synthesis[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Tattersall MH, et al. Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs. Eur J Clin Invest. 1975;5(2):191-202.

Chemical & Physical Properties

[ Density]:
1.922g/cm3

[ Molecular Formula ]:
C₁₀H₁₇N₂O₁₄P₃

[ Molecular Weight ]:
482.16800

[ Exact Mass ]:
481.98900

[ PSA ]:
273.57000

[ Index of Refraction ]:
1.604

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XP2084000

CHEMICAL NAME :: Thymidine 5'-(tetrahydrogen triphosphate)

CAS REGISTRY NUMBER :: 365-08-2

LAST UPDATED :: 199707

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H17-N2-O14-P3

MOLECULAR WEIGHT :: 482.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Unscheduled DNA synthesis

TEST SYSTEM :: Rodent - mouse Fibroblast

DOSE/DURATION :: 1 mmol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 29,797,1986

Precursor & DownStream

Precursor

DownStream

Related Compounds

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