1-BCP

Names

[ CAS No. ]:
34023-62-6

[ Name ]:
1-BCP

[Synonym ]:
1-BCP
1-piperonyloyl-piperidine
1,3-BYCP
1-Piperonyloyl-piperidin
BA 14

Biological Activity

[Description]:

1-BCP is a centrally active drug that modulates AMPA receptor gated currents. 1-BCP is a memory-enhancing agent[1][2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[Target]

AMPA receptor[1].

[References]

[1]. Arai A, et al. A centrally active drug that modulates AMPA receptor gated currents. Brain Res. 1994 Feb 28;638(1-2):343-6.

[2]. Desai MA, et al. 1-BCP, a memory-enhancing agent, selectively potentiates AMPA-induced [3H]norepinephrine release in rat hippocampal slices. Neuropharmacology. 1995 Feb;34(2):141-7.

Chemical & Physical Properties

[ Density]:
1.256g/cm3

[ Boiling Point ]:
406.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₃H₁₅NO₃

[ Molecular Weight ]:
233.26

[ Flash Point ]:
199.9ºC

[ Exact Mass ]:
233.10500

[ PSA ]:
38.77000

[ LogP ]:
1.97930

[ Index of Refraction ]:
1.587

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM4568000

CHEMICAL NAME :: Piperidine, 1-(1,3-benzodioxol-5-ylcarbonyl)-

CAS REGISTRY NUMBER :: 34023-62-6

BEILSTEIN REFERENCE NO. :: 0234640

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C13-H15-N-O3

MOLECULAR WEIGHT :: 233.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YAHOA3 Yakhak Hoe Chi. Journal of the Pharmaceutical Society. (Taehan Yakkakhoe, c/o College of Pharmacy, Seoul National Univ., Seoul 151, S. Korea) V.1- 1956(?)- Volume(issue)/page/year: 30,163,1986

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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