(-)-Gallocatechin

Names

[ Name ]:
(-)-Gallocatechin

[Synonym ]:
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,5,7-chromanetriol
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)chromane-3,5,7-triol
2H-1-Benzopyran-3,5,7-triol, 3,4-dihydro-2-(3,4,5-trihydroxyphenyl)-, (2S,3R)-
MFCD01632616
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
(2S,3R)-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
(2S,3R)-2-(3,4,5-Trihydroxyphenyl)chroman-3,5,7-triol
(-)-Gallocatechin
Gallocatechol

Biological Activity

[Description]:

(-)-Gallocatechin, an epimer of (-)-Epigallocatechin (EGC), is contained in various tea products. (-)-Gallocatechin has antioxidant activities[1][2][3].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Takagaki A, et, al. Biotransformation of (-)-epigallocatechin and (-)-gallocatechin by intestinal bacteria involved in isoflavone metabolism. Biol Pharm Bull. 2015;38(2):325-30.

[2]. Xu JZ, et, al. Comparison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br J Nutr. 2004 Jun;91(6):873-81.

[3]. Ikeda I, et, al. Heat-epimerized tea catechins rich in gallocatechin gallate and catechin gallate are more effective to inhibit cholesterol absorption than tea catechins rich in epigallocatechin gallate and epicatechin gallate. J Agric Food Chem. 2003 Dec 3;51(25):7303-7.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
685.6±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₄O₇

[ Molecular Weight ]:
306.267

[ Flash Point ]:
368.5±31.5 °C

[ Exact Mass ]:
306.073944

[ PSA ]:
130.61000

[ LogP ]:
-0.10

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.776

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 5 mg/mL with brief sonication

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Identification and quantification of phytochemicals in nutraceutical products from green tea by UHPLC-Orbitrap-MS.

Food Chem. 173 , 607-18, (2014)

A method has been developed and validated for the simultaneous detection and quantification of phytochemicals in nutraceutical products obtained from green tea. For that purpose, ultra-high performanc...

An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

J. Nat. Prod. 73 , 1193-5, (2010)

Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple fo...

Radical-scavenging activity of dietary phytophenols in combination with co-antioxidants using the induction period method.

Molecules 16(12) , 10457-70, (2011)

The radical-scavenging activity of dietary phytophenols has been investigated by many researches due to their antioxidant, anti-inflammatory and anticancer property but the radical-scavenging effect o...