Perfluorooctanoic Acid

Names

[ CAS No. ]:
335-67-1

[ Name ]:
Perfluorooctanoic Acid

[Synonym ]:
A 5717
[14C]-Perfluorooctanoic acid
nPFOA
Eftop EF 201
perfluorocaprylic acid
RARECHEM AL BO 0424
pentadecafluorocaprylic acid
Pentadecafluorooctanoic acid
octanoic acid, pentadecafluoro-
EF 201
Perfluoroctanoic acid
Perfluorooctanoic Acid
EINECS 206-397-9
Perfluoro-n-octanoic acid
PFOA,Perfluorocaprylic acid,Perfluorooctanoic acid
PFOA,Perfluorocaprylic acid
perfluorooctylcarboxylic acid
PFOA
MFCD00004174
Perfluorooctanoic Acid High Grade
Octanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro-
Pentadecafluorooctanoic Acid High Grade
PERFLUOROOCTANOATE
IPC-PFFA-8
Fluorad FC-26
n-Perfluorooctanoic acid
IPC-PFFA-8 HG

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
188.0±0.0 °C at 760 mmHg

[ Melting Point ]:
55-56 °C(lit.)

[ Molecular Formula ]:
C₈HF₁₅O₂

[ Molecular Weight ]:
414.068

[ Flash Point ]:
62.1±25.9 °C

[ Exact Mass ]:
413.973694

[ PSA ]:
37.30000

[ LogP ]:
7.75

[ Vapour Pressure ]:
0.3±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.289

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with bases, oxidizing agents, reducing agents.

[ Water Solubility ]:
3.4 g/L

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RH0781000

CHEMICAL NAME :: Octanoic acid, pentadecafluoro-

CAS REGISTRY NUMBER :: 335-67-1

BEILSTEIN REFERENCE NO. :: 1809678

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C8-H-F15-O2

MOLECULAR WEIGHT :: 414.09

WISWESSER LINE NOTATION :: QVXFFXFFXFFXFFXFFXFFXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 189 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 mg/kg/7D-I

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Biochemical - Metabolism (Intermediary) - lipids including transport

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 84 mg/kg/2W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1092 mg/kg/26W-C

TOXIC EFFECTS :: Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases

TYPE OF TEST :: DNA damage

MUTATION DATA

TEST SYSTEM :: Rodent - rat

DOSE/DURATION :: 168 mg/kg/2W (Continuous)

REFERENCE :: CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 57,55,1991

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302 + H332-H318-H351-H360D-H362-H372

[ Precautionary Statements ]:
P201-P260-P263-P280-P305 + P351 + P338 + P310-P308 + P313

[ Target Organs ]:
Liver

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S36/37

[ RIDADR ]:
UN 3261 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
RH0781000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29159080

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

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