2-Pyridylethylamine dihydrochloride
Names
[ CAS No. ]:
3343-39-3
[ Name ]:
2-Pyridylethylamine dihydrochloride
[Synonym ]:
2-PYRIDINEETHANAMINE DIHYDROCHLORIDE
2-Pyridylethylamine dihydrochloride
C7H10N2.2HCl
Biological Activity
[Description]:
2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.025g/cm3
[ Boiling Point ]:
207.9ºC at 760mmHg
[ Molecular Formula ]:
C7H12Cl2N2
[ Molecular Weight ]:
195.09
[ Flash Point ]:
100.6ºC
[ Exact Mass ]:
194.03800
[ PSA ]:
38.91000
[ LogP ]:
2.88710
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US1819170
- CHEMICAL NAME :
- Pyridine, 2-(2-aminoethyl)-, dihydrochloride
- CAS REGISTRY NUMBER :
- 3343-39-3
- LAST UPDATED :
- 198712
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H10-N2.2Cl-H
- MOLECULAR WEIGHT :
- 195.11
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg
- TOXIC EFFECTS :
- Behavioral - excitement Behavioral - muscle contraction or spasticity
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 30,178,1967