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HFI-142

Names

[ CAS No. ]:
332164-34-8

[ Name ]:
HFI-142

Biological Activity

[Description]:

HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a ki of 2.01 μM[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Aminopeptidase
Research Areas >> Neurological Disease

[Target]

ki: 2.01 μM (Insulin-regulated aminopeptidase)[1]


[References]

[1]. Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78(4):600-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C17H16N2O4

[ Molecular Weight ]:
312.32

Related Compounds