2-DEOXY-D-GLUCOSE 6-PHOSPHATE SODIUM SALT

Names

[ Name ]:
2-DEOXY-D-GLUCOSE 6-PHOSPHATE SODIUM SALT

[Synonym ]:
2-Deoxy-D-glucose 6-phosphate sodium salt

Biological Activity

[Description]:

2-Deoxy-D-glucose 6-phosphate disodium, a derivative of 2-Deoxy-D-glucose, is produced in mammalian cells by the action of hexokinase on 2-DG. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65(15):7023-30.

[2]. B Pajak, et al. 2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents. Int J Mol Sci. 2019 Dec 29;21(1):234.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆H₁₂NaO₈P

[ Molecular Weight ]:
266.11800

[ Exact Mass ]:
266.01700

[ PSA ]:
149.32000

Safety Information

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
23/24/25-36/37/38

[ Safety Phrases ]:
26-36/37/39-45

Related Compounds

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