RQIKIWFQNRRMKWKK

Names

[ Name ]:
RQIKIWFQNRRMKWKK

[Synonym ]:
RQIKIWFQNRRMKWKK
Penetratin
Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys

Biological Activity

[Description]:

DT-3 is a membrane-permeable protein kinase G Iα inhibitory peptide. DT-3 is a guanylyl cyclase? inhibitor and shows pharmacological blockade of the cGMP–PKG signalling[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase

[References]

[1]. Shinichi Takahashi, et al. Nitric oxide-cGMP-protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC6. J Physiol. 2008 Sep 1;586(17):4209-23.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀₄H₁₆₈N₃₄O₂₀S

[ Storage condition ]:
−20°C

Related Compounds

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