2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite

Names

[ Name ]:
2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite

Biological Activity

[Description]:

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₅₁FN₇O₇P

[ Molecular Weight ]:
875.94

[ Storage condition ]:
2-8℃