<Suppliers Price>

(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

Names

[ CAS No. ]:
319927-23-6

[ Name ]:
(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

[Synonym ]:
N-[(2S)-2-{[(2S)-2-({[(2S)-1-{N-[(2S)-2-{[(2S,3R)-2-{[(2S,3S)-2-Amino-1-hydroxy-3-methylpentylidene]amino}-1,3-dihydroxybutylidene]amino}-1,5-dihydroxy-5-iminopentylidene]-L-valyl}-2-pyrrolidinyl](hydroxy)methylene}amino)-1-hydroxy-3-phenylpropylidene]amino}-1,3-dihydroxypropylidene]-L-valine
L-Valine, N-[(2S)-2-[[(2S)-2-[[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S,3S)-2-amino-1-hydroxy-3-methylpentylidene]amino]-1,3-dihydroxybutylidene]amino]-1,5-dihydroxy-5-iminopentylidene]amino]-3-methyl-1-oxobutyl]-2-pyrrolidinyl]hydroxymethylene]amino]-1-hydroxy-3-phenylpropylidene]amino]-1,3-dihydroxypropylidene]-
(Des-Asp187)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse)

Biological Activity

[Description]:

Gp100:209-217 is a gp 100-derived human CTL epitope presented by HLA-A2. Gp100:209-217 is a polypeptide containing eight amino acids. Gp100:209-217 is a potent TGF-β inhibitor and blocks TGF-β signaling pathway[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Terabe M, et, al. Synergistic effect of TGF-β blockade and immunogenic agents on tumors. WO2006089251.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1071.5±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C42H67N9O12

[ Molecular Weight ]:
890.03400

[ Flash Point ]:
601.8±37.1 °C

[ Exact Mass ]:
889.49100

[ PSA ]:
341.78000

[ LogP ]:
5.99

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.621

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.