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Aloesin

Names

[ CAS No. ]:
30861-27-9

[ Name ]:
Aloesin

[Synonym ]:
Aloe resin B
4H-1-Benzopyran-4-one, 8-β-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-
Aloersin B
(1S)-1,5-Anhydro-1-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-chromen-8-yl]-D-glucitol
D-Glucitol, 1,5-anhydro-1-C-[7-hydroxy-5-methyl-4-oxo-2-(2-oxopropyl)-4H-1-benzopyran-8-yl]-, (1S)-
Aloesin

Biological Activity

[Description]:

Aloesin (Aloeresin) is an active constituent of the herb aloe vera and displays anti-inflammatory activity, ultraviolet protection, and antibacterium effects. Aloesin exerts its anticancer effect through the MAPK signaling pathway[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Zhang LQ, et al. Aloesin Suppresses Cell Growth and Metastasis in Ovarian Cancer SKOV3 Cells through the Inhibition of the MAPK Signaling Pathway. Anal Cell Pathol (Amst). 2017;2017:8158254.

[2]. Wahedi HM, et al. Aloesin from Aloe vera accelerates skin wound healing by modulating MAPK/Rho and Smad signaling pathways in vitro and in vivo. Phytomedicine. 2017 May 15;28:19-26.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
628.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H22O9

[ Molecular Weight ]:
394.373

[ Flash Point ]:
224.2±25.0 °C

[ Exact Mass ]:
394.126373

[ PSA ]:
157.66000

[ LogP ]:
0.64

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.637

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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