(2H16)Adamantane

Names

[ CAS No. ]:
30470-60-1

[ Name ]:
(2H16)Adamantane

[Synonym ]:
Adamantane-d16
(H)Adamantane
Tricyclo[3.3.1.1]decane-d
hexadecadeuterio-adamantane

Biological Activity

[Description]:

Adamantane-d16 is the deuterium labeled DL-Histidine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
187.1±7.0 °C at 760 mmHg

[ Melting Point ]:
209-212ºC (subl.)(lit.)

[ Molecular Formula ]:
C₁₀D₁₆

[ Molecular Weight ]:
152.33

[ Flash Point ]:
48.9±11.7 °C

[ Exact Mass ]:
152.225632

[ LogP ]:
4.22

[ Vapour Pressure ]:
0.9±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.517

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3