FLT3-IN-16

Names

[ Name ]:
FLT3-IN-16

Biological Activity

[Description]:

FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FLT3

[Target]

IC50: 1.1 μM (FLT3)[1]

[In Vitro]

FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM[1].

[References]

[1]. Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6.

Chemical & Physical Properties

[ Density]:
1.391±0.06 g/cm3(Predicted)

[ Boiling Point ]:
394.8±42.0 °C(Predicted)

[ Molecular Formula ]:
C₁₅H₁₅N₃O₂S

[ Molecular Weight ]:
301.36

[ Storage condition ]:
-20°C

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.