2-(Trimethylammonio)ethyl dodecyl phosphate

Names

[ Name ]:
2-(Trimethylammonio)ethyl dodecyl phosphate

[Synonym ]:
1-dodecyl phosphocholine
Dodecyl 2-(trimethylammonio)ethyl phosphate
12:0 PHOSPHOCHOLINE
odecyl phosphocholine
2-(Trimethylammonio)ethyl dodecyl phosphate
n-Dodecylphosphorylcholine
Ethanaminium, 2-[[(dodecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt
Dodecylphosphocholine
N-DODECYLPHOSPHOCHOLINE
Choline,hydroxide,dodecyl hydrogen phosphate,inner salt (8ci)
dodecylphosphatidylcholine
FOS-CHOLINE-12
Ethanaminium,2-[[(dodecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-,inner salt
dodecylphosphorylcholine

Biological Activity

[Description]:

Dodecylphosphocholine is a detergent widely utilized in NMR studies of membrane proteins[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Dodecylphosphocholine micelles can be used to characterize pore formation the influenza M2 transmembrane (M2TM) domain by NMR spectroscopy[2].

[References]

[1]. François Dehez, et al. Mitochondrial ADP/ATP Carrier in Dodecylphosphocholine Binds Cardiolipins with Non-native Affinity. Biophys J. 2017 Dec 5;113(11):2311-2315.

[2]. Sarah D Cady, et al. Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. J Am Chem Soc. 2011 Mar 30;133(12):4274-84.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₃₈NO₄P

[ Molecular Weight ]:
351.462

[ Exact Mass ]:
351.253845

[ PSA ]:
68.40000

[ LogP ]:
1.46

[ Storage condition ]:
-20°C

Safety Information

[ HS Code ]:
2923900090

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%