L-4-Nitrophenylalanine

Names

[ Name ]:
L-4-Nitrophenylalanine

[Synonym ]:
2-Amino-3-(4-nitrophenyl)propanoic acid
4-nitro-DL-phenylalanine
L-4-Nitrophe
4-Nitrophenylalanine
para-nitrophenylalanine
L-Phenylalanine, 4-nitro- (9CI)
p-Nitrophenylalanine
L-Phenylalanine, 4-nitro-
Nitrophenylalanine
4-14-00-01677 (Beilstein Handbook Reference)
DL-phenylalanine, 4-nitro-
L-p-Nitrophenylalanine
4-Nitro-DL-phenylalanine hydrate
EINECS 220-868-6
L-Phe(4-NO2)-OH
Alanine, 3-(p-nitrophenyl)-, L-
L-4- Nitrophenylalanine
3-(4-Nitrophenyl)-L-alanine
dl-p-Nitrophenylalanine
4-NITRO-DL-PHE-OH
4-NITRO-L-PHENYLANINEHYDRATE
H-P-NITRO-DL-PHE-OH
MFCD00007384
4-nitro Phenylalanine
Phenylalanine, 4-nitro-
DL-4-NO2-Phe-OH
p-Nitrophenylalanine, DL-
(2S)-2-amino-3-(4-nitrophenyl)propanoic acid
P-NITRO-DL-PHENYLALA

Biological Activity

[Description]:

H-DL-Phe(4-NO2)-OH is a phenylalanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-824.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
414.1±35.0 °C at 760 mmHg

[ Melting Point ]:
236-237 °C (dec.)(lit.)

[ Molecular Formula ]:
C₉H₁₀N₂O₄

[ Molecular Weight ]:
210.187

[ Flash Point ]:
204.2±25.9 °C

[ Exact Mass ]:
210.064056

[ PSA ]:
109.14000

[ LogP ]:
0.84

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
Store at RT.

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T: Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ Hazard Class ]:
6.1

Articles

Sensitive, soluble chromogenic substrates for HIV-1 proteinase.

J. Biol. Chem. 265 , 7733, (1990)

By replacement of the P1' residue in a capsid/nucleocapsid cleavage site mimic with 4-NO2-phenylalanine (Nph), an excellent chromogenic substrate, Lys-Ala-Arg-Val-Leu*Nph-Glu-Ala-Met, for HIV-1 protei...

Genetic incorporation of unnatural amino acids into proteins in Mycobacterium tuberculosis.

PLoS ONE 5(2) , e9354, (2010)

New tools are needed to study the intracellular pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), to facilitate new drug discovery and vaccine development. We have d...

Comparison of fluorescence reagents for simultaneous determination of hydroxylated phenylalanine and nitrated tyrosine by high-performance liquid chromatography with fluorescence detection.

Biomed. Chromatogr. 26(1) , 41-50, (2012)

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are well-known and important contributors to oxidative and nitrosative stress in several diseases. Hydroxylated phenylalanine and nitr...