BIORESMETHRIN
Names
[ CAS No. ]:
28434-01-7
[ Name ]:
BIORESMETHRIN
[Synonym ]:
6-HYDROXYFLAVONE-B-D-GLUCOSIDE
5-benzyl-3-furylmethyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
(5-benzylfuran-3-yl)methyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropane-1-carboxylate
biohanin A-7-glucoside
Bioresmethrin
d-trans-resmethrin
[5-(phenylmethyl)-3-furanyl]methyl (1R,3R)-2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate
5-benzyl-3-furylmethyl (1R)-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate
Chemical & Physical Properties
[ Density]:
1.111g/cm3
[ Boiling Point ]:
415.6ºC at 760mmHg
[ Melting Point ]:
32.5°C
[ Molecular Formula ]:
C22H26O3
[ Molecular Weight ]:
338.44000
[ Flash Point ]:
205.2ºC
[ Exact Mass ]:
338.18800
[ PSA ]:
39.44000
[ LogP ]:
5.15200
[ Index of Refraction ]:
1.573
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GZ1310500
- CHEMICAL NAME :
- Cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, (5-benzyl-3-furyl) methyl ester, d-trans-
- CAS REGISTRY NUMBER :
- 28434-01-7
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C22-H26-O3
- MOLECULAR WEIGHT :
- 338.48
- WISWESSER LINE NOTATION :
- T5OJ B1R& E1OV- BL3TJ A1 A1 C1UY1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1244 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5200 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 340 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - acute pulmonary edema
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 590 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - excitement Behavioral - ataxia
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Micronucleus test
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - mouse Leukocyte
- DOSE/DURATION :
- 120 umol/L
- REFERENCE :
- DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 10,291,1987
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H410
[ Precautionary Statements ]:
P273-P301 + P312 + P330-P391-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
N: Dangerous for the environment;
[ Risk Phrases ]:
50/53
[ Safety Phrases ]:
60-61
[ RIDADR ]:
UN 3082
[ RTECS ]:
GZ1310500
[ Packaging Group ]:
III
Articles
Toxicol. Appl. Pharmacol. 221(1) , 1-12, (2007)
Hydrolytic metabolism of pyrethroid insecticides in humans is one of the major catabolic pathways that clear these compounds from the body. Rodent models are often used to determine the disposition an...
In vitro covalent binding of cismethrin, bioresmethrin, and their common alcohol to hepatic proteins.Toxicol. Appl. Pharmacol. 77(1) , 11-8, (1985)
When [14C]Alcohol-labeled cismethrin, bioresmethrin, and 5-benzyl-3-furylmethyl alcohol (BFA) were incubated with rat liver S 9 homogenates or microsomes, a proportion of the radioactive compounds was...
Effect of bioresmethrin on mitochondrial ultrastructure and oxidative phosphorylation in the flight muscles of Chrysomya albiceps (Wied.) (Diptera: Calliphoridae).J. Egypt. Soc. Parasitol. 28(3) , 645-54, (1998)
The sublethal effect of bioresmethrin on the ultrastructure, oxidation and phosphorylation of flight muscle mitochondria in the blow fly Chrysomya albiceps which survived treatment of newly formed pup...