MALT1-IN-11

Names

[ CAS No. ]:
2812352-99-9

[ Name ]:
MALT1-IN-11

Biological Activity

[Description]:

MALT1-IN-11 (Example 151 in reference Patent) is a MALT1 protease inhibitor (IC50 < 10 nM). MALT1-IN-11 inhibits IL10 secretion with an IC50 of 10-100 nM. MALT1-IN-11 can be used for the research of cancer, autoimmune and inflammatory disorders[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> NF-κB >> MALT1
Research Areas >> Inflammation/Immunology

[In Vitro]

MALT1-IN-11 (Example 151, 24 h) 抑制 OCI-LY10 细胞中 IL10 的分泌[1]。

[References]

[1]. Shulu FENG, et al. Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disoders. Patent. WO2022164789.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H16F4N8O

[ Molecular Weight ]:
460.39

Related Compounds