1,2-Diundecanoyl-sn-glycero-3-phosphocholine

[ Molecular Formula ]:
C₃₀H₆₀NO₈P

[ Molecular Weight ]:
593.77300

[ Exact Mass ]:
593.40600

[ PSA ]:
121.00000

[ LogP ]:
7.78100

[ Storage condition ]:
-20°C

Germline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegans.

PLoS Genet. 10(12) , e1004829, (2014)

In C. elegans, removal of the germline extends lifespan significantly. We demonstrate that the nuclear hormone receptor, NHR-49, enables the response to this physiological change by increasing the exp...

DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans.

PLoS Genet. 12 , e1005788, (2016)

Elimination of the proliferating germline extends lifespan in C. elegans. This phenomenon provides a unique platform to understand how complex metazoans retain metabolic homeostasis when challenged wi...

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