TD-802

Names

[ CAS No. ]:
2760703-21-5

[ Name ]:
TD-802

Biological Activity

[Description]:

TD-802 (Compound 33c) is an androgen receptor (AR) PROTAC degrader with good microsomal stability. TD-802 has good antitumor efficacy in vivo and can be used for metastatic castration-resistant prostate cancer research[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC
Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. Takwale AD, et al. Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras. Eur J Med Chem. 2020 Dec 15;208:112769.

Chemical & Physical Properties

[ Molecular Formula ]:
C52H61ClN10O6

[ Molecular Weight ]:
957.56

Related Compounds