TYK2-IN-11

Names

[ CAS No. ]:
2757009-40-6

[ Name ]:
TYK2-IN-11

Biological Activity

[Description]:

TYK2-IN-11 (Compound 5B) is a selective Tyk-2 inhibitor with IC50s of 0.016 and 0.31 nM for TYK2-JH2 and JAK1-JH2, respectively. TYK2-IN-11 can be used for the research of inflammatory or autoimmune disease[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK
Signaling Pathways >> Epigenetics >> JAK
Signaling Pathways >> Stem Cell/Wnt >> JAK
Research Areas >> Inflammation/Immunology

[References]

[1]. Qiuwen WANG, et al. Tyk-2 inhibitor. WO2021259208A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H17N5O3S

[ Molecular Weight ]:
383.42

Related Compounds