DX3-213B

Names

[ Name ]:
DX3-213B

Biological Activity

[Description]:

DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC50=3.6 nM). DX3-213B impairs ATP generation (IC50=11 nM), and blocks MIA PaCa-2 cell growth (GI50=11 nM). DX3-213B is used for the research of the pancreatic cancer[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Xue D, et al. Multiparameter Optimization of Oxidative Phosphorylation Inhibitors for the Treatment of Pancreatic Cancer. J Med Chem. 2022;65(4):3404-3419.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₈F₂N₂O₅S₂

[ Molecular Weight ]:
478.57

Related Compounds

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