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GNE-9815

Names

[ CAS No. ]:
2729996-45-4

[ Name ]:
GNE-9815

Biological Activity

[Description]:

GNE-9815 is among the most highly kinase-selective RAF inhibitors targeting KRAS mutant cancers via combination treatment.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> MAPK/ERK Pathway >> Raf

[References]

[1]. Huestis MP, et al. Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor. ACS Med Chem Lett. 2021 Apr 21;12(5):791-797.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H22FN5O2

[ Molecular Weight ]:
455.48

Related Compounds