HIF-PHD-IN-2

Names

[ CAS No. ]:
2711720-45-3

[ Name ]:
HIF-PHD-IN-2

Biological Activity

[Description]:

HIF-PHD-IN-2 (compound 25) is a potent PHD inhibitor with IC50s of <100 nM for PHD1, PHD2 and PHD3, respectively[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[References]

[1]. Sabnis RW. Novel Compounds as PHD Inhibitors for Treating Heart, Lung, Liver, and Kidney Diseases. ACS Med Chem Lett. 2021;12(12):1868-1869. Published 2021 Nov 4.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₁₅N₅O₃S

[ Molecular Weight ]:
369.40

Related Compounds

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