5-Fluorotryptamine hydrochloride
Names
[ CAS No. ]:
2711-58-2
[ Name ]:
5-Fluorotryptamine hydrochloride
[Synonym ]:
5-Fluorotryptaminehydrochloride
2-(5-Fluoro-1H-indol-3-yl)ethanamine
1H-Indole-3-ethanamine, 5-fluoro-, monohydrochloride (9CI)
1H-Indole-3-ethanamine, 5-fluoro-
1H-Indole-3-ethanamine, 5-fluoro-, hydrochloride (1:1)
5-Fluorotryptamine hydrochloride
2-(5-fluoro-1H-indol-3-yl)ethanamine,hydrochloride
EINECS 220-307-5
MFCD00051081
2-(5-Fluoro-1H-indol-3-yl)ethanamine hydrochloride (1:1)
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
346.0±27.0 °C at 760 mmHg
[ Melting Point ]:
277-283
[ Molecular Formula ]:
C10H12ClFN2
[ Molecular Weight ]:
214.667
[ Flash Point ]:
163.0±23.7 °C
[ Exact Mass ]:
214.067307
[ PSA ]:
41.81000
[ LogP ]:
1.52
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.644
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL4055600
- CHEMICAL NAME :
- Indole, 3-(2-aminoethyl)-5-fluoro-, hydrochloride
- CAS REGISTRY NUMBER :
- 2711-58-2
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H11-F-N2.Cl-H
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 529 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - lacrimation Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- EXPEAM Experientia. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1945- Volume(issue)/page/year: 16,200,1960
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NL4055600
[ HS Code ]:
2942000000
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2942000000
Articles
Eur. J. Pharmacol. 580(3) , 291-7, (2008)
Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotry...
Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.Biomed. Chromatogr. 14(5) , 306-10, (2000)
A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as interna...
Thrombin: active-site topography.Ann. N. Y. Acad. Sci. 485 , 80-95, (1986)