n-methyl-4,4'-methylenedianiline

Names

[ Name ]:
n-methyl-4,4'-methylenedianiline

[Synonym ]:
4-((4-Aminophenyl)methyl)-N-methylbenzenamine
N-Methyl-4,4'-Methylendiamin
N-methyl-4,4'-diaminodiphenylmethane
4-(4-methylaminobenzyl)phenylamine
N-Methyl-4,4'-methylenedianiline
N-methyl-4,4'-MDA
ANILINE,N-METHYL-4,4'-METHYLENEDI
MFCD00192304

Chemical & Physical Properties

[ Density]:
1.113g/cm3

[ Boiling Point ]:
390.8ºC at 760mmHg

[ Melting Point ]:
61-63ºC(lit.)

[ Molecular Formula ]:
C₁₄H₁₆N₂

[ Molecular Weight ]:
212.29000

[ Flash Point ]:
224.5ºC

[ Exact Mass ]:
212.13100

[ PSA ]:
38.05000

[ LogP ]:
3.55550

[ Vapour Pressure ]:
2.58E-06mmHg at 25°C

[ Index of Refraction ]:
1.648

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY5700000

CHEMICAL NAME :: Aniline, N-methyl-4,4'-methylenedi-

CAS REGISTRY NUMBER :: 26628-67-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H16-N2

MOLECULAR WEIGHT :: 212.32

WISWESSER LINE NOTATION :: ZR D1R DM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 10 ug/plate

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 42,3475,1982

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
BY5700000

[ HS Code ]:
2921590090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921590090

[ Summary ]:
2921590090. other aromatic polyamines and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Disposition and metabolism of the carcinogen reduced Michler's ketone in rats.

Cancer Res. 42(9) , 3475-9, (1982)

Studies on the in vivo and in vitro disposition of 4,4'-[14C]-methylenebis(N,N-dimethyl)benzamine (reduced Michler's ketone, RMK) were performed. Osborne-Mendel rats retained, after 24 hr, 78% of a p....