3-INDOXYL SULFATE POTASSIUM SALT
Names
[ CAS No. ]:
2642-37-7
[ Name ]:
3-INDOXYL SULFATE POTASSIUM SALT
[Synonym ]:
Indoxyl sulfate potassium salt
Schwefelsaeure-mono-indol-3-ylester,Kalium-Verbindung
3-indolyl hydrogen sulfate potassium salt
potassium 1H-indol-3-yl sulfate
Urinary indican
Indol-3-yl sulfate,potassium salt
MFCD00037931
3-Indoxyl sulfate potassium salt
EINECS 220-145-5
sulfuric acid mono-indol-3-yl ester,potassium-compound
Potassium indol-3-yl sulfate
Potassium indol-3-yl sulphate
Indol-3-yl potassium sulfate
Indol-3-ol,potassium sulfate
Chemical & Physical Properties
[ Melting Point ]:
165 °C (dec.)(lit.)
[ Molecular Formula ]:
C8H6KNO4S
[ Molecular Weight ]:
251.30100
[ Exact Mass ]:
250.96500
[ PSA ]:
90.60000
[ LogP ]:
2.08770
[ Appearance of Characters ]:
light yellow
[ Storage condition ]:
−20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NM3200000
- CHEMICAL NAME :
- Indol-3-ol, hydrogen sulfate (ester), potassium salt
- CAS REGISTRY NUMBER :
- 2642-37-7
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C8-H6-N-O4-S.K
- MOLECULAR WEIGHT :
- 251.31
- WISWESSER LINE NOTATION :
- T56 BMJ DOSWO &-KA- &17/13
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3500 mg/kg/26W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - tumors
- REFERENCE :
- KLWOAZ Klinische Wochenscrift. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.1- 1922- Volume(issue)/page/year: 36,1056,1958
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NM3200000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
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Uremic toxin indoxyl 3-sulfate regulates the differentiation of Th2 but not of Th1 cells to lessen allergic asthma.Toxicol. Lett. 225(1) , 130-8, (2014)
Immune system dysfunctions including the increased Th1/Th2 ratio are common in chronic kidney disease (CKD) patients, and a wide variety of skin diseases including Th1-mediated uremic pruritis are ass...