TAK-802 hydrochloride
Names
[ CAS No. ]:
263248-36-8
[ Name ]:
TAK-802 hydrochloride
Biological Activity
[Description]:
A potent acetylcholinesterase (AChE) inhibitor with IC50 of 1.3 nM; exhibits high selectivity for acetylcholinesterase inhibition over butyrylcholinesterase inhibition; increases rhythmic bladder contractions in Guinea pigs and rats without affecting the basal intravesical pressure. Other Indication Phase 2 Discontinued
[References]
References 1. Ishichi Y, et al. Bioorg Med Chem. 2005 Mar 15;13(6):1901-11. 2. Nagabukuro H, et al. Eur J Pharmacol. 2004 Feb 6;485(1-3):299-305. 3. Nagabukuro H, et al. Eur J Pharmacol. 2004 Jun 28;494(2-3):225-32. View Related Products by Target Acetylcholinesterase (AChE) Other Indication
Chemical & Physical Properties
[ Molecular Formula ]:
C26H30ClFN2O2
[ Molecular Weight ]:
456.986