NG-497
Names
[ CAS No. ]:
2598242-66-9
[ Name ]:
NG-497
Biological Activity
[Description]:
NG-497 is a selective human adipose triglyceride lipase (ATGL) inhibitor that targets the enzymatically active patatin-like domain of human ATGL. NG-497 has potential value for tumor research[1].
[Related Catalog]:
[In Vitro]
NG-497 可选择性地使人和非人灵长类动物 ATGL 失活,但不会使结构和功能相关的脂质水解酶失活,并以剂量依赖性和可逆的方式消除人类脂肪细胞的脂肪分解[1]。 NG-497(40 μM, 80 min)可以减少 HepG2 细胞的脂解依赖性呼吸,并且不会通过脱靶效应损害线粒体功能[1]。
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H21NO4
[ Molecular Weight ]:
315.36