PRMT5-IN-11

Names

[ Name ]:
PRMT5-IN-11

Biological Activity

[Description]:

PRMT5-IN-11 is a promising structure-dependent inhibition of the protein methyltransferase PRMT5:MEP50 complex in the (sub)micromolar range.

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Histone Methyltransferase

Research Areas >> Others

[References]

[1]. Jouffroy L, et al. Regio- and Stereoselective Synthesis of C-4' Spirocyclobutyl Ribofuranose Scaffolds and Their Use as Biologically Active Nucleoside Analogues. Org Lett. 2021 Nov 19;23(22):8828-8833.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₇N₅O₄

[ Molecular Weight ]:
307.31

Related Compounds

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