Ascochlorin A

Names

[ CAS No. ]:
2550720-02-8

[ Name ]:
Ascochlorin A

Biological Activity

[Description]:

Ascochlorin A is a novel and potent hDHODH inhibitor (KD = 3.29 μM) for treatment of triple-negative breast cancer.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

[References]

[1]. Luo X, et al. Exploring Marine-Derived Ascochlorins as Novel Human Dihydroorotate Dehydrogenase Inhibitors for Treatment of Triple-Negative Breast Cancer. J Med Chem. 2021 Sep 23;64(18):13918-13932.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₃₁ClO₄

[ Molecular Weight ]:
406.94

Related Compounds

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