adipic acid d-10

Names

[ CAS No. ]:
25373-21-1

[ Name ]:
adipic acid d-10

[Synonym ]:
Decadeuterio-adipinsaeure
Hexanedioic-d acid-d
MFCD00190459
(H)Hexane(H)dioic acid
decadeuterio-adipic acid
Deuterated adipic acid,Hexanedioic acid-d10
adipic acid d-10
decadeuterio-hexanedioic acid
adipic-d8 acid-d2
D10-adipic acid
Hexanedioic acid-d10

Biological Activity

[Description]:

Adipic acid-d10 is the deuterium labeled Adipic acid[1]. Adipic acid is found to be associated with HMG-CoA lyase deficiency, carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency, and medium Chain acyl-CoA dehydrogenase deficiency, which are inborn errors of metabolism[2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. G.Frauendienst-Egger, Friedrich K. Trefz (2017). MetaGene: Metabolic & Genetic Information Center. METAGENE consortium.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
338.5±15.0 °C at 760 mmHg

[ Melting Point ]:
151-154ºC(lit.)

[ Molecular Formula ]:
C6D10O4

[ Molecular Weight ]:
156.203

[ Flash Point ]:
196.1±0.0 °C

[ Exact Mass ]:
156.120682

[ PSA ]:
74.60000

[ LogP ]:
0.08

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.476

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant

[ Risk Phrases ]:
R20/22-36

[ Safety Phrases ]:
26-36

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Related Compounds